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Send InquiryArticaine Hydrochloride Or Articaine Hcl
Articaine Hydrochloride Or Articaine Hcl Specification
- Properties
- Formula: C H N O S HClMolecular Weight: 320.84 g/molStructure: Unlike other amides, articaine features a unique thiophene ring (instead of a benzene ring) and an additional ester group.Lipid Solubility: The thiophene ring enhances lipid solubility, allowing the drug to easily diffuse through nerve sheaths and tissue.Melting Point: 177 178 CSolubility: Soluble in water (up to 20 mg/mL)
- Active Ingredient
- Articaine hydrochloride is an amide-type local anesthetic and the primary active ingredient in injectable dental anesthetics (often formulated with epinephrine as a vasoconstrictor). It is highly prized in dentistry for its rapid onset and high lipid solubility, allowing it to easily diffuse through tissues
- Grade
- IP BP USP
- State
- Powder
- Color
- WHITE
- Molecular Formula
- C H N O S HCl
- Classification
- other
- Purity(%)
- 99.9
- Product Name
- Articaine Hydrochloride
- CAS No
- 23964-57-0
Articaine Hydrochloride Or Articaine Hcl Trade Information
- Minimum Order Quantity
- 1 Kilograms
- FOB Port
- NAHVA SHEVA
- Payment Terms
- Cash Advance (CA), Cash in Advance (CID)
- Supply Ability
- 100 Kilograms Per Day
- Delivery Time
- 3 Days
- Sample Available
- Yes
- Packaging Details
- HDPE DRUM
- Main Export Market(s)
- North America, South America, Eastern Europe, Asia, Australia, Central America, Middle East, Africa, Western Europe
- Main Domestic Market
- All India
- Certifications
- ALL
About Articaine Hydrochloride Or Articaine Hcl
Articaine HCl (Articaine hydrochloride) is a fast-acting, amide-type local anesthetic primarily used in dental procedures for local, infiltrative, or conductive anesthesia. It is unique among local anesthetics because its chemical structure includes a thiophene ring, which increases its lipid solubility and tissue penetration. Quick Facts & Properties- Primary Use: Dental extractions, restorations, and other oral surgeries.
- Mechanism of Action: It reversibly blocks voltage-gated sodium channels in peripheral nerves, preventing the transmission of pain signals.
- Formulation: Commonly combined with epinephrine (a vasoconstrictor) in 4% solutions (\(40\text{ mg/mL}\)) to slow systemic absorption and prolong the duration of the anesthetic.
- Metabolism: It is hydrolyzed rapidly by plasma esterases, which shortens its systemic exposure and reduces the risk of drug toxicity compared to other amides.
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